Deleting Locked Files

You can delete locked files with the RemoveOnReboot utility. You can install the RemoveOnReboot utility from here.
After you delete a locked file, you need to delete all the references to the file in Windows registry.

To delete a locked file:

1. Right-click on the file and select Send To -> Remove on Next Reboot on the menu.
2. Restart your computer.

     3.  The file will be deleted on restart.


Note:In the case of complex viruses that can replicate themselves, malware files can reappear in the same locations even after you have deleted those files and restarted your computer.